Ingabe i-hydroxypropyl methylcellulose ne-hypromellose ziyefana?

I-Hydroxypropyl methylcellulose (HPMC) kanye ne-hypromellose ziyinhlanganisela efanayo, futhi amagama avame ukusetshenziswa ngokushintshana. Lawa amagama ayinkimbinkimbi ezinhlobo ezivamile zama-polymers asekelwe ku-cellulose anezinhlobonhlobo zezicelo ezimbonini ezihlukahlukene ezihlanganisa ezemithi, ukudla nezimonyo.

1.Isakhiwo samakhemikhali kanye nokwakheka:

IHydroxypropylmethylcellulose (HPMC) iwukuguqulwa kokwenziwa kwe-cellulose, i-polymer yemvelo etholakala ezindongeni zamaseli ezitshalo. Isakhiwo samakhemikhali se-HPMC sitholwa ngokwethula i-hydroxypropyl kanye namaqembu e-methyl ngesisekelo se-cellulose. Iqembu le-hydroxypropyl lenza i-cellulose incibilike kakhulu emanzini, futhi iqembu le-methyl lithuthukisa ukuzinza kwalo futhi linciphise ukusebenza kabusha kwalo.

2. Inqubo yokukhiqiza:

Ukukhiqizwa kwe-hydroxypropyl methylcellulose kubandakanya ukwelapha i-cellulose nge-propylene oxide ukwethula amaqembu e-hydroxypropyl bese nge-methyl chloride ukuze kwengezwe amaqembu e-methyl. I-degree of substitution (DS) ye-hydroxypropyl ne-methyl ingashintshwa phakathi nenqubo yokukhiqiza, okuholela emabangeni ahlukene e-HPMC anezakhiwo ezahlukene.

3. Izakhiwo zomzimba:

I-HPMC iyimpushana emhlophe ukuya kokumhlophe kancane, ayinaphunga futhi ayinambitheki. Izakhiwo zayo ezingokomzimba, ezifana ne-viscosity kanye ne-solubility, zincike ezingeni lokushintshwa kanye nesisindo samangqamuzana we-polymer. Ngaphansi kwezimo ezijwayelekile, incibilika kalula emanzini, yakha isixazululo esisobala nesingenambala.

4. Izinjongo zokwelashwa:

Enye yezicelo eziyinhloko ze-HPMC isembonini yezemithi. Isetshenziswa kabanzi njenge-excipient yezemithi futhi idlala izindima ezihlukahlukene ekulungiseleleni imithi. I-HPMC ivamise ukutholakala kumafomu wemithamo eqinile yomlomo njengamaphilisi, amaphilisi, namaphilisi. Isebenza njenge-binder, disintegrant, ne-ejenti yokukhululwa elawulwayo, enikela ekuzinzeni okuphelele kanye nokuba khona kwe-bioavailability yomuthi.

5. Iqhaza emalungiselelweni okukhishwa okulawulwayo:

Ikhono le-HPMC ukwenza amajeli ezixazululweni ezinamanzi alenza libe yigugu ekwakhiweni kwemithi ekhishwa okulawulwayo. Ngokushintsha i-viscosity kanye nezakhiwo ze-gel-forming, ososayensi bezemithi bangakwazi ukulawula izinga lokukhululwa kwezithako ezisebenzayo, ngaleyo ndlela bazuze isenzo sezidakamizwa esiqhubekayo futhi eside.

6. Isicelo embonini yokudla:

Embonini yokudla, i-HPMC isetshenziswa njenge-thickener, stabilizer kanye ne-emulsifier. Ithuthukisa ukuthungwa kwezinhlobonhlobo zokudla, okuhlanganisa amasoso, amasobho nemikhiqizo yobisi. Ukwengeza, i-HPMC isetshenziswa ekubhakeni okungenagluten ukuze kuthuthukiswe ukwakheka kanye nezakhiwo zokuswakama zemikhiqizo engenayo i-gluten.

7. Izinto zokwakha nezinto zokwakha:

I-HPMC isetshenziswa embonini yezokwakha emikhiqizweni efana nezinamatheliso zamathayela, amapulastele asekelwe kusimende kanye nezinto ezenziwe ngegypsum. Ithuthukisa ukucutshungulwa, ukugcinwa kwamanzi kanye nezakhiwo zokunamathela zale mikhiqizo.

8. Izimonyo nemikhiqizo yokunakekelwa komuntu siqu:

I-Hypromellose futhi iyisithako esivamile kuzimonyo nemikhiqizo yokunakekelwa komuntu siqu. Isetshenziswa kuma-creams, lotions kanye nama-shampoos ngenxa yokuqina kwayo kanye nezindawo zokuzinzisa. Ukwengeza, kusiza ukuthuthukisa ukuthungwa jikelele nomuzwa womkhiqizo.

9. Ukumbozwa kwefilimu emithini yemithi:

I-HPMC isetshenziswa kabanzi embonini yezemithi ukuze kuhlanganiswe ifilimu yamaphilisi. Amaphilisi ahlanganiswe nefilimu anikeza ukubukeka okuthuthukisiwe, ukufihla ukunambitheka nokuvikelwa ezicini zemvelo. Amafilimu e-HPMC ahlinzeka ngokunamathela okubushelelezi nokufana okufanayo, athuthukisa ikhwalithi yonkana yomkhiqizo wezidakamizwa.

13. Isiphetho:

I-Hydroxypropyl methylcellulose (HPMC) kanye ne-hypromellose kubhekisela ku-polymer esekelwe ku-cellulose esebenza ngezinhlobonhlobo zemithi, ukudla, izimonyo, kanye nokwakhiwa. Izici zayo eziyingqayizivele, njengokuncibilika, ukuzinza kanye nokubola kwe-biodegradability, kunomthelela ekusetshenzisweni kwayo kabanzi. Ukuguquguquka kwe-HPMC ezimbonini ezahlukene kugqamisa ukubaluleka kwayo njengento esebenza ngezinto eziningi, futhi iyaqhubeka kabusha.ukusesha nokuthuthukisa kungase kwembule izinhlelo zokusebenza ezengeziwe esikhathini esizayo.

Lokhu kuhlola okuphelele kuhlose ukuhlinzeka ngokuqonda okuningiliziwe kwe-hydroxypropyl methylcellulose ne-hypromellose, kucaciswe ukubaluleka kwazo emikhakheni eyahlukene, nokucacisa indima yazo ekubumbeni imikhiqizo eminingi kanye nokwakheka.