IHydroxypropyl methylcellulose (HPMC) iyisithako samakhemikhali esisebenza ngezindlela eziningi esisetshenziswa kakhulu embonini yezimonyo. Ivame ukusetshenziswa njenge-adhesive ngenxa yokuncibilika kwamanzi okuhle kakhulu, ukulungiswa kwe-viscosity kanye nekhono lokwenza ifilimu yokuzivikela. Kumafomula ezimonyo, i-HPMC idlala kakhulu indima yokunamathisela ukuze kuqinisekiswe ukuthi izithako zezimonyo zingasatshalaliswa ngokulinganayo futhi zigcine ukuzinza kwazo.
1. Isakhiwo samangqamuzana kanye nezakhiwo zokunamathela ze-HPMC
I-HPMC iwumphumela we-non-ionic cellulose otholwe ngokuguqulwa kwamakhemikhali kwe-cellulose yemvelo. Isakhiwo sayo samangqamuzana sihlanganisa amaqembu amaningi e-hydroxyl kanye ne-methyl kanye ne-hydroxypropyl. Lawa maqembu asebenzayo ane-hydrophilicity enhle kanye ne-hydrophobicity, evumela i-HPMC ukuthi yenze isixazululo se-colloidal ngamanzi noma i-organic solvents, futhi ihlanganyele nezinye izithako ngokusebenzisa amandla e-intermolecular afana ne-hydrogen bond, ngaleyo ndlela ibonisa ukunamathela okuhle kakhulu. I-HPMC idlala indima yokuhlanganisa izithako ezihlukahlukene kwifomula ndawonye ngokwandisa i-viscosity yesistimu futhi yakhe ifilimu enamathelayo ku-substrate, ikakhulukazi idlala indima ebalulekile ezinhlelweni ze-multiphase.
2. Ukusetshenziswa kwe-HPMC njenge-adhesive ezimonyoni
Umthelela wokunamathela we-HPMC ezimonyoni ubonakala ikakhulukazi kulezi zici ezilandelayo:
Ukusetshenziswa kwefomula engangeni manzi: Ezimonyoni ezingangeni manzi (ezifana ne-mascara engangeni manzi, i-eyeliner, njll.), i-HPMC ithuthukisa ukunamathela kwefomula ngokwenza ifilimu elivikelayo elizinzile, ukuze ukunamathela kwezimonyo esikhumbeni noma ezinweleni kuthuthukiswe. Ngesikhathi esifanayo, le filimu inezici ezingenawo amanzi, esiza umkhiqizo uhlale uzinzile lapho ubhekene nomjuluko noma umswakama, ngaleyo ndlela uthuthukise ukuqina komkhiqizo.
I-Adhesive yezimonyo eziyimpushana: Ezimonyoni eziyimpushana ezicindezelwe njengempushana ecindezelwe, ukushaqeka, nesithunzi samehlo, i-HPMC njengenamathela ingahlanganisa ngempumelelo izingxenye zempushana ukuze zakhe ifomu eliqinile elinamandla athile nokuzinza, igweme impushana ukuthi ingawi noma indize ngesikhathi. sebenzisa. Ngaphezu kwalokho, kungase futhi kuthuthukise ukushelela kwemikhiqizo ye-powder, okwenza kube lula ukuyisebenzisa ngokulinganayo uma uyisebenzisa.
Ukusetshenziswa emikhiqizweni yokunakekelwa kwesikhumba: I-HPMC ijwayele ukusetshenziswa njengento enamathelayo emikhiqizweni yokunakekelwa kwesikhumba, ikakhulukazi emikhiqizweni enjengamaski obuso nezigcobo. Ingaqinisekisa ukuthi izithako ezisebenzayo zisakazwa ngokulinganayo ebusweni besikhumba futhi zenze ifilimu yokuzivikela ngokwandisa i-viscosity yomkhiqizo, ngaleyo ndlela ithuthukise ukusebenza kahle nokuzwakala komkhiqizo.
Iqhaza emikhiqizweni yokwenza isitayela: Emikhiqizweni yokwenza isitayela efana nejeli yezinwele nesifutho sesitayela, i-HPMC ingasiza umkhiqizo wenze ifilimu yokwenza isitayela ezinweleni, futhi ilungise izinwele ndawonye ngokusebenzisa i-viscosity yazo ukuze kugcinwe ukuzinza nokuqina kwekhanda lezinwele. Ngaphezu kwalokho, ukuthamba kwe-HPMC nakho kwenza izinwele zibe mancane amathuba okuba ziqine, okwandisa ukunethezeka komkhiqizo.
3. Izinzuzo ze-HPMC njenge-adhesive
Ikhono elihle lokulungiswa kwe-viscosity: I-HPMC inokunyibilika okuphezulu kanye ne-viscosity eguquguqukayo emanzini, futhi ingakhetha i-HPMC yama-viscosity ahlukene ngokuya ngezidingo zokuzuza umphumela wefomula ongcono kakhulu. Umehluko wayo we-viscosity ekugxilweni okuhlukene uyivumela ukuthi isetshenziswe kalula kuzimonyo ezihlukahlukene. Isibonelo, i-HPMC ene-viscosity ephansi ingasetshenziswa emikhiqizweni yesifutho, kuyilapho i-HPMC ene-viscosity ephezulu ifanele ukhilimu noma imikhiqizo yejeli.
Ukuzinza nokuhambisana: I-HPMC inokuqina okuhle kwamakhemikhali, izinzile ezindaweni ezihlukene ze-pH, futhi akulula ukusabela nezinye izithako ezisebenzayo kufomula. Ngaphezu kwalokho, iphinde ibe nokuzinza okuphezulu kokushisa nokuqina kokukhanya, futhi akulula ukubola ngaphansi kwezinga lokushisa eliphezulu noma ukukhanya kwelanga, okwenza i-HPMC ibe inketho ekahle yamafomula ezinhlobonhlobo zezimonyo.
Ukuphepha nokungacasuli: I-HPMC isuselwa ku-cellulose yemvelo futhi inokuhambisana ne-biocompatibility ephezulu. Ngokuvamile akubangeli ukucasuka kwesikhumba noma ukungezwani komzimba. Ngakho-ke, isetshenziswa kabanzi ezinhlotsheni ezahlukene zezimonyo futhi ifanele abantu abanesikhumba esibucayi. Ifilimu eyakhayo esikhumbeni nayo iyaphefumula futhi ngeke ivimbe izimbotshana, iqinisekise ukuthi isikhumba singakwazi ukuphefumula ngokujwayelekile.
Thuthukisa ukuthinta nokuzwakala kwefomula: Ngaphezu kokuba isibophezelo, i-HPMC ingaphinda inikeze umkhiqizo umuzwa omuhle. Emikhiqizweni yokunakekelwa kwesikhumba, ingenza ukuthungwa komkhiqizo kube silky futhi bushelelezi, futhi kusize izithako ukuthi zisetshenziswe futhi zimunceke ngokulinganayo. Emikhiqizweni yezimonyo, ingathuthukisa i-ductility ye-powder, okwenza umkhiqizo uvumelane nesikhumba kangcono, ngaleyo ndlela uthuthukise umphumela wokwenza izimonyo.
4. Ukubambisana phakathi kwe-HPMC nezinye izithako
I-HPMC ivamise ukusetshenziswa ngokuhlangana nezinye izithako (ezifana namafutha, ama-silicone, njll.) ukuthuthukisa ukusebenza okuphelele kwamafomula ezimonyo. Isibonelo, emikhiqizweni equkethe ama-wax noma uwoyela, i-HPMC ingasonga ngokuzinzile amafutha noma ama-wax ku-matrix ngokusebenzisa izakhiwo zayo zefilimu nokunamathela ukuze kugwenywe ukuhlukaniswa kwengxenye, ngaleyo ndlela ithuthukise ukuzinza nokuthungwa komkhiqizo.
I-HPMC ingasetshenziswa futhi ngokubambisana nama-thickeners nama-gelling agents, njenge-carbomer ne-xanthan gum, ukuze kuthuthukiswe ukunamathela nokuzinza komkhiqizo. Lo mphumela we-synergistic uvumela i-HPMC ukuthi ibonise ukuguquguquka okuhle kohlelo lokusebenza kumafomula ezimonyo eziyinkimbinkimbi.
5. Ukuthuthukiswa kwesikhathi esizayo kwe-HPMC emkhakheni wezimonyo
Njengoba abathengi benezidingo eziphakeme neziphakeme zemvelo, ukuphepha nokusebenza kwezithako zezimonyo, i-HPMC, njengento esebenzayo etholakala ku-cellulose yemvelo, izoba nethuba elibanzi lokufaka isicelo kumafomula ezimonyo zesikhathi esizayo. Ngokuthuthuka kobuchwepheshe, ukwakheka kwamangqamuzana kanye nezakhiwo zomzimba ze-HPMC kungabuye kuthuthukiswe ukuze kuhlangatshezwane nezidingo zokwakheka eziyinkimbinkimbi neziyinkimbinkimbi, njengokuthambisa okusezingeni eliphezulu, ukulwa nokuguga, ukuvikela ilanga, njll.
Njengento enamathelayo ebalulekile kuzimonyo, i-HPMC iqinisekisa ukuzinza kwezithako zomkhiqizo, ukuthungwa okufanayo kanye nomphumela wokusetshenziswa ngokusebenzisa ukulawulwa kwayo okuhle kakhulu kwe-viscosity, ikhono lokwenza ifilimu nokuhambisana. Ukusetshenziswa kwayo okubanzi kanye nokusebenza okuhlukahlukene kuyenza ibe isithako esibaluleke kakhulu kumafomula esimanje sezimonyo. Ngokuzayo, i-HPMC izoqhubeka nokubamba iqhaza elibalulekile ocwaningweni nasekuthuthukisweni kwezimonyo zemvelo nezimonyo ezisebenzayo.
Isikhathi sokuthumela: Sep-26-2024