IHydroxypropylmethylcellulose (HPMC) iyi-ether cellulose esetshenziswa kakhulu ezimbonini ezahlukahlukene ngenxa yezakhiwo zayo eziyingqayizivele kanye nokuhlukahluka.I-polymer engenabuthi, encibilika emanzini encibilika kuwo womabili amanzi abandayo nashisayo.Iwumsebenzi obalulekile osetshenziswa njenge-thickener, binder, stabilizer, emulsifier, kanye nefilimu ngaphambilini ezinhlelweni ezahlukahlukene ezifana nemboni yezokudla, imithi, ukwakha, nezimonyo.
Enye yezinto ezibalulekile ze-HPMC ububanzi bayo be-viscosity.I-viscosity ye-HPMC incike ezintweni eziningana ezifana nezinga lokushintshwa, isisindo samangqamuzana nokugxila.Ngakho-ke, i-HPMC ingasetshenziswa ezinhlobonhlobo zezinhlelo zokusebenza ezidinga amazinga e-viscosity ahlukene.Isibonelo, i-HPMC ene-viscosity ephezulu ivamise ukusetshenziswa njenge-thickener kanye ne-stabilizer ekudleni, kuyilapho i-HPMC ene-viscosity ephansi isetshenziswa embonini yezemithi njengesihlanganisi kanye ne-tablet coating.
Ukuhlanzeka kwe-HPMC nakho kuyisici esibalulekile.Imvamisa iza ngamamaki ahlukene okuhlanzeka asukela ku-99% kuya ku-99.9%.Amabanga aphezulu wokuhlanzeka ngokuvamile akhethwa imboni yezemithi, enemithetho eqinile mayelana nekhwalithi yezinto ezingavuthiwe.Ukuhlanzeka okuphezulu kwe-HPMC kusiza ukuqinisekisa ikhwalithi engcono kakhulu yomkhiqizo wokugcina.Izinga lokuhlanzeka liphinde lithinte izakhiwo ze-HPMC ezifana ne-viscosity, ukuncibilika, kanye ne-gelation.Ngokuvamile, amazinga aphezulu okuhlanzeka athuthukisa izici zokusebenza.
Ngokungeziwe ku-viscosity nobumsulwa, kukhona ezinye izici ezibalulekile okufanele uzicabangele lapho ukhetha i-HPMC efanele yohlelo lokusebenza oluthile.Lokhu kufaka phakathi ubukhulu bezinhlayiyana, indawo engaphezulu, umswakama kanye nezinga lokushintsha.Usayizi wezinhlayiya nendawo engaphezulu ye-HPMC kungase kuthinte ukunyibilika kwayo, kuyilapho okuqukethwe komswakama kuthinta ukuzinza nempilo yeshelufu yayo.Kubalulekile ukukhetha izinga elilungile lokushintsha, okungukuthi ingxenye ehlobene ye-hydroxypropyl kanye ne-methyl substituent ku-molecule ye-HPMC.Iziqu eziphakeme zokushintsha zingaholela ekwandeni kokuncibilika kwamanzi kanye ne-viscosity ethuthukisiwe, kuyilapho amadigri aphansi okushintsha angaholela ekuthuthukisweni kwezakhiwo zokwenza ifilimu.
imboni yokudla
Embonini yokudla, i-HPMC ivamise ukusetshenziswa njenge-thickener, emulsifier and stabilizer emikhiqizweni eyahlukene efana namasoso, amasobho, okokugqoka, imikhiqizo yobisi nezimpahla ezibhakiwe.I-HPMC ithuthukisa ukuthungwa kokudla ngokunikeza ukuvumelana okubushelelezi, okukhilimu nokufana okufanayo.Kuyasiza futhi ukuvimbela izithako ekuhlukaneni, ngaleyo ndlela andise impilo yeshalofu yokudla.
Enye yezinto ezibalulekile ze-HPMC embonini yokudla amandla ayo okugcina i-viscosity yomkhiqizo emazingeni okushisa aphakeme, njengalapho upheka futhi ungadli.Ukuzinza kwezinga lokushisa eliphezulu kwe-HPMC kuyivumela ukuthi isetshenziswe ekudleni okunezinga lokushisa eliphezulu njengemikhiqizo esemathinini noma eqinile eshalofini.
Imboni yezemithi
Embonini yezemithi, i-HPMC ivame ukusetshenziswa njenge-binder, i-disintegrant, i-ejenti yokugqoka ithebhulethi, i-ejenti yokukhululwa elawulwayo, njll. emalungiselelweni ahlukahlukene emithi.I-HPMC ikhethwa ngaphezu kwezinye izinto ezinamathelayo ngoba ayinabo ubuthi futhi iyancibilika emanzini ashisayo nabandayo.Amandla okuncibilika emanzini ashisayo nabandayo awusizo ikakhulukazi kugranulation emanzi, indlela evamile yokukhiqiza amaphilisi.
I-HPMC iphinde isetshenziswe njenge-disintegrant yamaphilisi.Kuyasiza ukuhlephula amaphilisi abe yizicucu ezincane, okuthuthukisa izinga lomuthi omuncwa ngalo emzimbeni.Ngaphezu kwalokho, i-HPMC ivame ukusetshenziswa njenge-ejenti yokuhlanganisa ngenxa yezakhiwo zayo zokwenza ifilimu.Ivikela ithebhulethi ezintweni zemvelo, ngaleyo ndlela yandise impilo yeshalofu.
Bekezela
Embonini yezokwakha, i-HPMC isetshenziselwa ukwenza ngcono ukusebenza nokusebenza kwemikhiqizo kasimende ehlukahlukene efana nodaka, ama-grouts namaplasta.I-HPMC isebenza njenge-thickener, ithuthukisa ukunamathela, futhi inikeza izakhiwo zokugcina amanzi kumxube.Ikhono le-HPMC lokwenza ifilimu yokuvikela lisiza futhi ukuvimbela amanzi ukuthi angangeni kumatrix kasimende, athuthukise ukuqina.I-viscosity ye-HPMC idlala indima ebalulekile ekusebenzeni kwengxube.Ngakho-ke, ngokuya ngesicelo, amabanga ahlukene we-viscosity we-HPMC asetshenziswa.
yezimonyo
Embonini yezimonyo, i-HPMC isetshenziswa njenge-thickener, stabilizer, kanye nefilimu yangaphambili emikhiqizweni eyahlukene njengama-shampoos, ama-conditioner, nama-lotions.I-HPMC ithuthukisa ukuthungwa nokuvumelana kwezimonyo, inikeze isiphetho esibushelelezi, esinokhilimu.Iphinde ithuthukise ukuzinza komkhiqizo kanye nempilo yeshalofu ngokuvimbela ukuhlukaniswa kwezithako.Ukwengeza, izakhiwo zefilimu ze-HPMC zinikeza umgoqo ovikelayo osiza ukugcina umswakama, ngaleyo ndlela uvimbele ukoma.
Ekuphetheni
IHydroxypropyl methylcellulose inohlu olubanzi lwezidingo ze-viscosity nobumsulwa.Kuyimpahla eluhlaza esebenzayo esetshenziswa kabanzi ezimbonini ezahlukahlukene njengokudla, imithi, ukwakhiwa, kanye nezimonyo.Ibanga elibanzi le-viscosity livumela i-HPMC ukuthi isetshenziswe ezinhlelweni ezihlukahlukene ezidinga amazinga e-viscosity ahlukene.Amazinga aphezulu okuhlanzeka abalulekile embonini yezemithi, enemithetho eqinile mayelana nekhwalithi yezinto ezingavuthiwe.I-HPMC ibalulekile ekusebenzeni kwemikhiqizo eminingi, ngakho ukucatshangelwa kwe-viscosity efanele kanye nezinga lokuhlanzeka kubalulekile.
Isikhathi sokuthumela: Sep-06-2023