Ingabe i-HPMC i-hydrophobic noma i-hydrophilic?

IHydroxypropyl methylcellulose (HPMC) iyi-polymer esebenza ngezindlela eziningi enezinto zombili ze-hydrophobic kanye ne-hydrophilic, iyenza ihluke ekusetshenzisweni okuhlukahlukene kuzo zonke izimboni ezahlukahlukene. Ukuze siqonde i-hydrophobicity kanye ne-hydrophilicity ye-HPMC, sidinga ukutadisha isakhiwo sayo, izakhiwo kanye nokusetshenziswa kwayo ngokujulile.

Isakhiwo se-hydroxypropyl methylcellulose:

I-HPMC iphuma ku-cellulose, i-polymer yemvelo etholakala ezindongeni zamaseli ezitshalo. Ukuguqulwa kwe-cellulose kuhilela ukwethulwa kwamaqembu e-hydroxypropyl kanye ne-methyl kumgogodla we-cellulose. Lokhu kuguqulwa kushintsha izakhiwo ze-polymer, kunikeza izakhiwo ezithile ezizuzisa uhla olubanzi lwezinhlelo zokusebenza.

I-Hydrophilicity ye-HPMC:

I-Hydroxy:

I-HPMC iqukethe amaqembu e-hydroxypropyl futhi iyi-hydrophilic. Lawa maqembu e-hydroxyl anokusondelana okuphezulu kwama-molecule amanzi ngenxa yokuhlangana kwe-hydrogen.

Iqembu le-Hydroxypropyl lingakha izibopho ze-hydrogen ngama-molecule wamanzi, okwenza i-HPMC inyibilike emanzini ngokwezinga elithile.

i-methyl:

Nakuba iqembu le-methyl lifaka isandla ku-hydrophobicity yonke ye-molecule, aliphikisani ne-hydrophilicity yeqembu le-hydroxypropyl.

Iqembu le-methyl alifani ne-polar, kodwa ukuba khona kweqembu le-hydroxypropyl kunquma umlingiswa we-hydrophilic.

I-Hydrophobicity ye-HPMC:

i-methyl:

Amaqembu e-methyl ku-HPMC anquma ngokwezinga elithile i-hydrophobicity yayo.

Nakuba kungeyona i-hydrophobic njengamanye ama-polymers okwenziwa ngokugcwele, ukuba khona kwamaqembu e-methyl kunciphisa i-hydrophilicity iyonke ye-HPMC.

Izakhiwo zokwakha ifilimu:

I-HPMC yaziwa ngezakhiwo zayo zokwenza ifilimu futhi ivamise ukuxhashazwa kwezemithi nezimonyo. I-Hydrophobicity inomthelela ekwakhiweni kwefilimu evikelayo.

Ukusebenzelana nezinto ezingezona ezomhlaba:

Kwezinye izinhlelo zokusebenza, i-HPMC ingasebenzisana nezinto ezingezona ezingxenyeni ezizungezile ngenxa ye-hydrophobicity yayo ngokwengxenye. Le ndawo ibalulekile ezinhlelweni zokulethwa kwezidakamizwa embonini yezemithi.

Izicelo ze-HPMC:

umuthi:

I-HPMC isetshenziswa kakhulu ekwenziweni kwemithi njengesihlanganisi, ifilimu yangaphambili, kanye nesilungisi se-viscosity. Ikhono layo lokwenza ifilimu lisiza ukukhishwa okulawulwayo kwezidakamizwa.

Isetshenziswa ngomlomo kumafomu wesilinganiso esiqinile njengamaphilisi namaphilisi.

Imboni yezokwakha:

Emkhakheni wokwakha, i-HPMC isetshenziswa emikhiqizweni esekwe usimende ukuthuthukisa ukusebenza, ukugcinwa kwamanzi kanye nokunamathela.

I-Hydrophilicity isiza ukugcina amanzi, kuyilapho i-hydrophobicity isiza ukuthuthukisa ukunamathela.

imboni yokudla:

I-HPMC isetshenziswa njenge-ejenti yokuqina kanye ne-gelling embonini yokudla. Imvelo yayo ye-hydrophilic isiza ukwakha ama-gel azinzile futhi ilawule i-viscosity yemikhiqizo yokudla.

izimonyo:

Ekwenziweni kwezimonyo, i-HPMC isetshenziswa emikhiqizweni efana nokhilimu kanye nezinto zokugcoba ngenxa yezakhiwo zayo zokwakha ifilimu nokujiya.

I-Hydrophilicity iqinisekisa ukugeleza okuhle kwesikhumba.

Ekuphetheni:

I-HPMC iyi-polymer ene-hydrophilic ne-hydrophobic. Ibhalansi phakathi kwamaqembu e-hydroxypropyl kanye ne-methyl esakhiweni sayo ikunikeza ukuguquguquka okuyingqayizivele, okuyivumela ukuthi ibe nezinhlelo eziningi ezahlukene. Ukuqonda lezi zakhiwo kubalulekile ekwakhekeni kwe-HPMC ekusetshenzisweni okuthile ezimbonini ezihlukene, lapho ikhono le-HPMC lokusebenzelana namanzi nezinto ezingezona ezomhlaba lisetshenziselwa izinjongo ezihlukahlukene.