I-HPMC noma i-hydroxypropyl methylcellulose iyinto eguquguqukayo esetshenziswa ezimbonini ezahlukahlukene ezihlanganisa ezemithi, izimonyo nokudla. Isetshenziswa kabanzi njenge-thickener ne-emulsifier, futhi i-viscosity yayo iyashintsha kuye ngezinga lokushisa elivezwa kulo. Kulesi sihloko, sizogxila ebudlelwaneni phakathi kwe-viscosity nezinga lokushisa ku-HPMC.
I-viscosity ichazwa njengesilinganiso sokumelana noketshezi ukugeleza. I-HPMC into eqinile kancane isilinganiso sayo sokumelana sincike ezintweni ezihlukahlukene, okuhlanganisa izinga lokushisa. Ukuze siqonde ubudlelwano phakathi kwe-viscosity nezinga lokushisa ku-HPMC, okokuqala sidinga ukwazi ukuthi into yakhekeka kanjani nokuthi yenziwa ngani.
I-HPMC isuselwa ku-cellulose, i-polymer eyenzeka ngokwemvelo ezitshalweni. Ukukhiqiza i-HPMC, i-cellulose idinga ukushintshwa amakhemikhali nge-propylene oxide ne-methyl chloride. Lokhu kuguqulwa kuholela ekwakhekeni kwamaqembu e-hydroxypropyl kanye ne-methyl ether ochungechungeni lwe-cellulose. Umphumela uba into eqinile engancibilikisiwe emanzini nasezincibilikiseni eziphilayo futhi isetshenziswa ezinhlobonhlobo zezicelo, okuhlanganisa njengokumboza amaphilisi nanjenge-ejenti yokuqina kokudla, phakathi kokunye.
I-viscosity ye-HPMC incike ekugxilweni kwento kanye nezinga lokushisa lapho ivezwa khona. Ngokuvamile, i-viscosity ye-HPMC iyancipha ngokugxila okukhulayo. Lokhu kusho ukuthi ukugxila okuphezulu kwe-HPMC kubangela ama-viscosities aphansi futhi ngokuphambene nalokho.
Nokho, ubudlelwano obuphambene phakathi kwe-viscosity nezinga lokushisa buyinkimbinkimbi kakhulu. Njengoba kushiwo ngaphambili, i-viscosity ye-HPMC iyanda ngokuncipha kwezinga lokushisa. Lokhu kusho ukuthi uma i-HPMC ingaphansi kwamazinga okushisa aphansi, amandla ayo okugeleza ayancipha futhi iba ne-viscous. Ngokufanayo, lapho i-HPMC ingaphansi kwamazinga okushisa aphezulu, amandla ayo okugeleza ayanda futhi i-viscosity yayo iyancipha.
Kunezici ezihlukahlukene ezithinta ubudlelwano phakathi kwezinga lokushisa kanye ne-viscosity ku-HPMC. Isibonelo, ezinye izinyibilikisi ezikhona oketshezini zingathinta i-viscosity, kanjalo ne-pH yoketshezi. Nokho, ngokuvamile, kunobudlelwano obuphambene phakathi kwe-viscosity nezinga lokushisa ku-HPMC ngenxa yomphumela wokushisa ekubopheni i-hydrogen nokusebenzisana kwamangqamuzana amaketanga e-cellulose ku-HPMC.
Uma i-HPMC ingaphansi kwamazinga okushisa aphansi, amaketanga e-cellulose aba aqinile, okuholela ekwandeni kwe-hydrogen bonding. Lawa mabhondi e-hydrogen abangela ukuthi ukuphikiswa kwento kugeleze, ngaleyo ndlela kwandise i-viscosity yayo. Ngokuphambene, lapho ama-HPMC engaphansi kwamazinga okushisa aphezulu, amaketanga e-cellulose ashintshashintsha kakhulu, okuholele ekunciphiseni kwamabhondi e-hydrogen. Lokhu kunciphisa ukumelana kwento ukugeleza, okuholela ekubonakaleni okuphansi kwe-viscosity.
Kuyaphawuleka ukuthi nakuba ngokuvamile kukhona ubudlelwano obuphambene phakathi kwe-viscosity nezinga lokushisa le-HPMC, lokhu akuhlali kunjalo kuzo zonke izinhlobo ze-HPMC. Ubudlelwano obuqondile phakathi kwe-viscosity nezinga lokushisa bungase buhluke kuye ngenqubo yokukhiqiza kanye nebanga elithile le-HPMC elisetshenzisiwe.
I-HPMC iyisithako esisebenza ngezinto eziningi esisetshenziswa kabanzi ezimbonini ezehlukene ngenxa yokuqina kwayo kanye nezakhiwo ze-emulsifying. I-viscosity ye-HPMC incike ezintweni ezimbalwa, okuhlanganisa ukugxila kwento kanye nezinga lokushisa lapho ivezwa khona. Ngokuvamile, i-viscosity ye-HPMC ihambisana ngokuphambene nezinga lokushisa, okusho ukuthi njengoba izinga lokushisa liyancipha, i-viscosity iyanda. Lokhu kungenxa yomphumela wezinga lokushisa ekubopheni i-hydrogen nokusebenzisana kwamangqamuzana amaketango e-cellulose ngaphakathi kwe-HPMC.
Isikhathi sokuthumela: Sep-08-2023