IHydroxypropyl methylcellulose (HPMC) iyisengezo samakhemikhali esisetshenziswa kakhulu ekukhiqizeni udaka lwengxube emanzi. Le nhlanganisela ye-cellulose ether inezakhiwo ezikhethekile ezithuthukisa ukusebenza, ukuqina nokusebenza kwezinsimbi. Umsebenzi oyinhloko we-HPMC ukukhulisa ukugcinwa kwamanzi nokunamathela, ngaleyo ndlela kuthuthukise ikhono lokubopha likadaka.
1. Thuthukisa ukusebenza
Ukusebenza kodaka oluxubekile olumanzi kubhekisela emandleni awo okuphathwa kalula futhi athululwe ngesikhathi sokwakhiwa. Lesi yisici esibalulekile sokuqinisekisa ukuthi udaka kulula ukuxutshwa, ukuthululela kanye nokwenza. I-HPMC isebenza njenge-plasticizer ngaleyo ndlela inikeze inani elifanele lokugcinwa kwamanzi kanye ne-viscosity kudaka. Ngokungezwa kwe-HPMC, udaka luba ne-viscous kakhulu, luyivumele ukuthi inamathele futhi ibophe kangcono.
Umthelela we-HPMC ekusebenzeni kodaka ungabangelwa ikhono layo lokujiya nokuguqula i-rheology yengxube. Ngokwandisa i-viscosity yengxube, i-HPMC iyenza igeleze kangcono futhi inciphise noma yikuphi ukuthambekela kokuhlukanisa noma ukopha. I-rheology ethuthukisiwe yengxube iphinde isize ukunciphisa i-viscosity yodaka, okwenza kube lula ukusebenza nayo.
2. Khulisa ukugcinwa kwamanzi
Ukugcinwa kwamanzi kungenye yezinto ezibaluleke kakhulu zodaka lwengxube emanzi. Kubhekiselwa emandleni odaka ukugcina amanzi isikhathi eside. Udaka ludinga ukugcinwa kwamanzi okwanele ukuze lukhulise amandla futhi luvimbele ukushwabana nokuqhekeka ngesikhathi somiswa.
I-HPMC ithuthukisa ukugcinwa kwamanzi kodaka lwengxube emanzi ngokulawula ukumuncwa kanye nokukhishwa kwamanzi kungxube. Yakha ifilimu elincanyana elizungeze izinhlayiya zikasimende, livimbele ukuba libambe amanzi amaningi futhi ngaleyo ndlela ligcine ukuhambisana kwengxube. Ifilimu iphinde isize ukubambezela ukuhwamuka kwamanzi kungxube, ngaleyo ndlela yelule isikhathi sokusebenza sodaka.
3. Khulisa ukunamathela
I-Adhesion yikhono lodaka lokubopha nokunamathela ku-substrate. Lokhu kuyisici esibalulekile ekuqinisekiseni ukuthi udaka luhlala endaweni futhi aluhlukani nendawo olufakwa kulo. I-HPMC ithuthukisa ukunamathela kodaka lwengxube emanzi ngokwandisa ukuhlangana kwengxube, ngaleyo ndlela ithuthukise amandla ayo okubopha.
I-HPMC ifinyelela lokhu ngokwenza ifilimu elincanyana elizungeze izinhlayiya zikasimende, esiza ukuthuthukisa amandla omshini wodaka. Ifilimu iphinde isebenze njengesithiyo, ivimbele udaka ekuhlukaneni ne-substrate. Ukunamathela kodaka okuthuthukisiwe kuthuthukisa ukuqina nokuthembeka kokwakhiwa.
Ekuphetheni
Ukwengezwa kwe-HPMC osikeni bengxube emanzi kunemiphumela eminingana enenzuzo ekusebenzeni, ukuqina kanye nokusebenza kwengxube. Kwenza ngcono ukugcinwa kwamanzi, ukusebenza kahle nokunamathela, okwenza udaka luhlangane kakhulu, luphathe kalula futhi luthembeke kakhudlwana. Lezi zakhiwo zenza i-HPMC ibe isithako samakhemikhali esibalulekile ekukhiqizeni udaka lwengxube emanzi.
Isikhathi sokuthumela: Sep-15-2023