IHydroxypropylmethylcellulose (HPMC) kanye ne-carboxymethylcellulose (CMC) yizinhlobo ezimbili ezihlukene zama-polymers asetshenziswa ekwakhiweni kokuwa kwamehlo, ngokuvamile asetshenziselwa ukukhulula izimpawu zamehlo omile. Nakuba zabelana ngokufana okuthile, lezi zinhlanganisela ezimbili zinomehluko ocacile ekwakhekeni kwamakhemikhali, izakhiwo, indlela yokusebenza, kanye nezicelo zomtholampilo.
I-Hydroxypropyl methylcellulose (HPMC) amaconsi iso:
1.Isakhiwo samakhemikhali:
I-HPMC iwukuphuma kokwenziwa kwe-cellulose, i-polymer yemvelo etholakala ezindongeni zamaseli ezitshalo.
Amaqembu e-Hydroxypropyl kanye ne-methyl ethulwa esakhiweni se-cellulose, enikeza i-HPMC izakhiwo eziyingqayizivele.
2. I-Viscosity kanye ne-rheology:
Amaconsi iso e-HPMC ngokuvamile ane-viscosity ephakeme kunamanye amaconsi amaningi agcobayo.
I-viscosity eyengeziwe isiza amaconsi ukuthi ahlale endaweni ye-ocular isikhathi eside, anikeze ukukhululeka okude.
3. Indlela yokwenza:
I-HPMC yenza ungqimba oluvikelayo nolugcobayo endaweni ye-ocular, inciphisa ukungqubuzana futhi ithuthukise ukuqina kwefilimu yezinyembezi.
Kuyasiza ekudambiseni izimpawu zamehlo omile ngokuvimbela ukuhwamuka okukhulu kwezinyembezi.
4. Isicelo somtholampilo:
Amaconsi eso e-HPMC ajwayele ukusetshenziselwa ukwelapha isifo samehlo esomile.
Zibuye zisetshenziswe ekuhlinzeni kwe-ophthalmic kanye nokuhlinzwa ukuze kugcinwe i-corneal hydration.
5. Izinzuzo:
Ngenxa ye-viscosity ephakeme, inganweba isikhathi sokuhlala endaweni ye-ocular.
Ikhulula ngokuphumelelayo izimpawu zamehlo omile futhi inikeza induduzo.
6. Okubi:
Abanye abantu bangase babe nombono olufifi ngokushesha ngemva kokufakwa ngenxa yokwanda kwe-viscosity.
I-Carboxymethylcellulose (CMC) amaconsi iso:
1.Isakhiwo samakhemikhali:
I-CMC ingenye i-cellulose derivative eguqulwe ngamaqembu e-carboxymethyl.
Ukwethulwa kweqembu le-carboxymethyl kuthuthukisa ukunyibilika kwamanzi, okwenza i-CMC ibe i-polymer encibilika emanzini.
2. I-Viscosity kanye ne-rheology:
Amaconsi iso e-CMC ngokuvamile ane-viscosity ephansi uma kuqhathaniswa namaconsi eso e-HPMC.
I-viscosity ephansi ivumela ukufakwa kalula nokusabalalisa ngokushesha phezu kwendawo ye-ocular.
3. Indlela yokwenza:
I-CMC isebenza njengesithambiso nesithobisayo, ithuthukisa ukuzinza kwefilimu yezinyembezi.
Isiza ekudambiseni izimpawu zamehlo omile ngokukhuthaza ukugcinwa komswakama endaweni yamehlo.
4. Isicelo somtholampilo:
Amaconsi iso e-CMC asetshenziswa kabanzi ukukhulula izimpawu zamehlo omile.
Ngokuvamile zinconywa kubantu abane-eye syndrome eyomile emaphakathi kuya komaphakathi.
5. Izinzuzo:
Ngenxa ye-viscosity yayo ephansi, isakazeka ngokushesha futhi kulula ukuconsa.
Ngempumelelo futhi ngokushesha kukhulula izimpawu zamehlo omile.
6. Okubi:
Umthamo ovamile ungase udingeke uma kuqhathaniswa nokwakheka okuphezulu kwe-viscosity.
Amanye amalungiselelo angase abe nesikhathi esifushane sokusebenza endaweni ye-ocular.
Ukuhlaziya okuqhathanisayo:
1. I-Viscosity:
I-HPMC ine-viscosity ephezulu, ehlinzeka ngokukhululeka okuhlala isikhathi eside kanye nokuvikelwa okuzinzile.
I-CMC ine-viscosity ephansi, evumela ukusabalala ngokushesha kanye nokufaka kalula.
2. Ubude besenzo:
I-HPMC ngokuvamile inikeza ubude besikhathi besenzo ngenxa yokubonakala kwayo okuphezulu.
I-CMC ingase idinge umthamo ovamile, ikakhulukazi ezimeni zeso elomile kakhulu.
3. Ukunethezeka kwesiguli:
Abanye abantu bangathola ukuthi amaconsi iso e-HPMC ekuqaleni abangela ukufiphala kwesikhashana kombono ngenxa ye-viscosity yawo ephezulu.
Amaconsi iso e-CMC ngokuvamile abekezelelwa kahle futhi abangela ukufiphala okuncane kokuqala.
4. Izincomo zomtholampilo:
I-HPMC ivame ukutuswa kubantu abane-syndrome yeso elomile elimaphakathi noma elinzima.
I-CMC ivamise ukusetshenziselwa amehlo omile amaphakathi ukuya kwamaphakathi kanye nakulabo abakhetha ifomula ye-viscous encane.
I-Hydroxypropylmethylcellulose (HPMC) kanye ne-carboxymethylcellulose (CMC) amaconsi wamehlo kokubili izinketho ezibalulekile ekwelapheni izimpawu zamehlo omile. Ukukhetha phakathi kwalokhu okubili kuncike ekuthandeni komuntu siqu kwesiguli, ubukhali beso elomile, kanye nesikhathi esifiswayo sokuthatha isinyathelo. I-viscosity ephakeme ye-HPMC inikeza isivikelo esihlala isikhathi eside, kuyilapho i-viscosity ephansi ye-CMC inikeza ukukhululeka okusheshayo futhi ingase ibe inketho yokuqala kubantu abazwela ukubona okufiphele. Odokotela bamehlo kanye nodokotela bamehlo bavame ukucabangela lezi zici lapho bekhetha amaconsi eso okugcoba afaneleka kakhulu ezigulini zabo, aklanyelwe ukuthuthukisa ukunethezeka futhi adambise ngempumelelo izimpawu zamehlo omile.
Isikhathi sokuthumela: Dec-25-2023