IHydroxypropylmethylcellulose (HPMC) iphuma ku-cellulose evamise ukusetshenziswa ezimbonini ezahlukene, okuhlanganisa ezemithi, ezokwakha nezokudla. I-viscosity yayo ingahluka ngokuya ngezinto ezifana nesisindo sayo samangqamuzana, izinga lokushintshwa, kanye nokugxila kwesixazululo.
Isingeniso se-Hydroxypropyl Methylcellulose (HPMC)
IHydroxypropyl methylcellulose i-semi-synthetic polymer etholwe ngokuguqulwa kwamakhemikhali ku-cellulose. Ngenxa yezakhiwo zayo eziyingqayizivele, isetshenziswa kabanzi njenge-thickener, i-ejenti ye-gelling, ifilimu yangaphambili kanye ne-stabilizer ezinhlelweni ezihlukahlukene.
Ukwakheka kwamangqamuzana nokwakheka
I-HPMC iqukethe umgogodla we-cellulose one-hydroxypropyl kanye ne-methoxy substituents. I-degree of substitution (DS) ibhekisela enanini elimaphakathi leyunithi ngayinye ye-anhydroglucose kuketango le-cellulose. Inani elithile le-DS lithinta izakhiwo ezingokoqobo nezamakhemikhali ze-HPMC.
HPMC viscosity
I-Viscosity iyipharamitha ebalulekile ye-HPMC, ikakhulukazi ezinhlelweni ezisebenzisa izici zayo zokujiya kanye ne-gelling.
I-viscosity yezixazululo ze-HPMC ithintwa izici eziningi:
1. Isisindo samangqamuzana
Isisindo samangqamuzana e-HPMC sithinta i-viscosity yayo. Ngokuvamile, i-HPMCs enesisindo esiphezulu se-molecular ivame ukukhiqiza izixazululo eziphezulu ze-viscosity. Kunamabanga ahlukene e-HPMC emakethe, ngalinye linobubanzi balo besisindo samangqamuzana eliqokiwe.
2. Iziqu zokushintsha (DS)
Amanani e-DS e-hydroxypropyl namaqembu e-methoxy athinta ukuncibilika kanye ne-viscosity ye-HPMC. Amanani aphezulu e-DS ngokuvamile aphumela ekwandeni kokuncibilika kwamanzi kanye nezixazululo ezishubile.
3. Ukugxila
Ukugxila kwe-HPMC kusixazululo kuyisici esibalulekile esithinta i-viscosity. Njengoba ukugxila kuyanda, i-viscosity ivame ukwanda. Lobu budlelwano buvame ukuchazwa yi-equation ye-Krieger-Dougherty.
4. Izinga lokushisa
Izinga lokushisa liphinde lithinte i-viscosity yezixazululo ze-HPMC. Ngokuvamile, i-viscosity iyancipha njengoba izinga lokushisa likhuphuka.
Izindawo zokufaka izicelo
Ezemithi: I-HPMC ivamise ukusetshenziswa ekwenziweni kwemithi, okuhlanganisa amaphilisi nezisombululo zamehlo, lapho ukukhululwa okulawulwayo kanye ne-viscosity kubalulekile.
Ezokwakha: Embonini yezokwakha, i-HPMC isetshenziswa njengokujiya emikhiqizweni esekwe usimende ukuthuthukisa ukusebenza kanye nokugcinwa kwamanzi.
Imboni Yokudla: I-HPMC isetshenziswa njenge-thickener, stabilizer kanye ne-emulsifier ezinhlelweni zokudla.
I-viscosity ye-hydroxypropyl methylcellulose iyimpahla eyinkimbinkimbi ethintekayo ngenxa yezinto eziningi ezifana nesisindo samangqamuzana, izinga lokushintsha, ukugxila kanye nezinga lokushisa. Amabanga ahlukene e-HPMC ayatholakala ukuze afanele izinhlelo zokusebenza ezithile, futhi abakhiqizi bahlinzeka ngamashidi edatha obuchwepheshe acacisa uhla lwe-viscosity lwebanga ngalinye ngaphansi kwezimo ezihlukahlukene. Abacwaningi nabakhi kufanele bacabangele lezi zici ukuze bahlanganise izakhiwo ze-HPMC ukuze bahlangabezane nezimfuneko zezinhlelo zabo ezihlosiwe.
Isikhathi sokuthumela: Jan-20-2024