Ukuze siqhathanise i-CMC (i-carboxymethylcellulose) ne-HPMC (i-hydroxypropylmethylcellulose), sidinga ukuqonda izakhiwo zazo, izinhlelo zokusebenza, izinzuzo, ukungalungi, kanye nezimo zokusebenzisa ezingase zibe khona.Kokubili okuphuma ku-cellulose kusetshenziswa kabanzi ezimbonini ezahlukahlukene, kufaka phakathi ezemithi, ukudla, izimonyo nezokwakha.Ngayinye inezinto ezihlukile ezibenza bafanelekele izinhloso ezahlukene.Masenze ukuqhathanisa okujulile ukuze sibone ukuthi iyiphi engcono ezimeni ezahlukene.
1. Incazelo nesakhiwo:
I-CMC (carboxymethylcellulose): I-CMC iphuma ku-cellulose encibilika emanzini ekhiqizwa ukusabela kwe-cellulose ne-chloroacetic acid.Iqukethe amaqembu e-carboxymethyl (-CH2-COOH) ahlanganiswe namanye amaqembu e-hydroxyl we-glucopyranose monomers akha umgogodla we-cellulose.
I-HPMC (i-hydroxypropyl methylcellulose): I-HPMC futhi iphuma ku-cellulose encibilika emanzini ekhiqizwa ngokwelapha i-cellulose nge-propylene oxide ne-methyl chloride.Iqukethe i-hydroxypropyl kanye namaqembu e-methoxy axhunywe kumgogodla we-cellulose.
2. Ukunyibilika:
I-CMC: Incibilika kakhulu emanzini, yakha isixazululo esisobala, ne-viscous.Ibonisa ukuziphatha kokugeleza kwe-pseudoplastic, okusho ukuthi i-viscosity yayo iyancipha ngaphansi kwengcindezi ye-shear.
I-HPMC: Iphinde inyibilike emanzini, yakha isixazululo se-viscous kancane kune-CMC.Iphinde ibonise ukuziphatha kwe-pseudoplastic.
3.Izakhiwo ze-Rheological:
I-CMC: Ibonisa ukuziphatha kokugunda kwe-shear, okusho ukuthi i-viscosity yayo iyehla ngokwenyuka kwezinga lokugunda.Le ndawo iyenza ifanelekele ukusetshenziswa lapho ukujiya kuyadingeka kodwa isixazululo sidinga ukugeleza kalula ngaphansi kokugunda, njengamapende, okokuhlanza kanye nemithi.
I-HPMC: ibonisa ukuziphatha okufanayo kwe-rheological ku-CMC, kodwa i-viscosity yayo ngokuvamile iphezulu ekugxilweni okuphansi.Inezinto ezingcono zokwenza ifilimu, okuyenza ifaneleke izinhlelo zokusebenza ezifana nama-coatings, ama-adhesives kanye nokukhishwa okulawulwayo kwemithi yokwenziwa kwemithi.
4. Ukuzinza:
I-CMC: Ngokuvamile izinzile phezu kwebanga elibanzi le-pH nezinga lokushisa.Ingakwazi ukubekezelela amazinga amaphakathi ama-electrolyte.
I-HPMC: Izinze kakhulu kune-CMC ngaphansi kwezimo ezine-acidic, kodwa ingase ithole i-hydrolysis ngaphansi kwezimo ze-alkaline.Futhi iyazwela kuma-divalent cations, angabangela i-gelation noma imvula.
5. Isicelo:
I-CMC: isetshenziswa kakhulu njenge-thickener, stabilizer kanye ne-ejenti yokugcina amanzi ekudleni (okufana no-ayisikhilimu, isoso), imithi (njengamaphilisi, ukumiswa) nezimboni zezimonyo (ezifana nokhilimu, okokugcoba).
I-HPMC: Isetshenziswa kakhulu ezintweni zokwakha (isb., izinto zokunamathisela zamathayela kasimende, ukhonkolo, udaka), imithi (isb, amaphilisi akhishwa okulawulwayo, amalungiselelo e-ophthalmic), nezimonyo (isb, amaconsi amehlo, imikhiqizo yokunakekelwa kwesikhumba).
6. Ubuthi nokuphepha:
I-CMC: Ivamise ukubonwa njengephephile (i-GRAS) yizinkampani ezilawulayo uma isetshenziswa ngaphakathi kwemikhawulo ethile ekudleni nasezinhlelweni zemithi.I-biodegradable futhi ayinabo ubuthi.
I-HPMC: Iphinde ithathwe njengephephile ukuthi isetshenziswe ngaphakathi kwemikhawulo enconyiwe.I-biocompatible futhi isetshenziswa kabanzi emkhakheni wezokwelapha njenge-ejenti yokukhululwa elawulwayo kanye nesibophezelo sethebhulethi.
7. Izindleko Nokutholakala:
I-CMC: Ivamise ukubiza kakhulu kune-HPMC.Itholakala kalula kubahlinzeki abahlukahlukene emhlabeni jikelele.
I-HPMC: Ibiza kancane ngenxa yenqubo yokukhiqiza futhi ngezinye izikhathi ukunikezwa okulinganiselwe okuvela kubahlinzeki abathile.
8. Umthelela wemvelo:
I-CMC: I-Biodegradable, etholakala ezinsizeni ezivuselelekayo (cellulose).Kubhekwa njengobungani bemvelo.
I-HPMC: Iphinde ibe yi-biodegradable futhi isuselwa ku-cellulose, ngakho-ke futhi inobungani bemvelo.
Kokubili i-CMC ne-HPMC zinezakhiwo ezihlukile ezizenza izithasiselo ezibalulekile ezimbonini eziningi.Ukukhetha phakathi kwabo kuncike ezidingweni ezithile zohlelo lokusebenza ezifana ne-solubility, viscosity, ukuzinza nokucatshangelwa kwezindleko.Ngokuvamile, i-CMC ingakhethwa ngenxa yezindleko zayo eziphansi, ukuzinza okubanzi kwe-pH, nokufaneleka kokudla nezimonyo zokusebenza.I-HPMC, ngakolunye uhlangothi, ingase ithandeke ngenxa ye-viscosity yayo ephezulu, izakhiwo ezingcono zokwenza amafilimu, kanye nokusetshenziswa kwemithi nezinto zokwakha.Ekugcineni, ukukhetha kufanele kusekelwe ekucabangeni okuphelele kwalezi zici kanye nokuhambisana nokusetshenziswa okuhlosiwe.
Isikhathi sokuthumela: Feb-21-2024