Ukuze siqhathanise i-CMC (i-carboxymethylcellulose) ne-HPMC (i-hydroxypropylmethylcellulose), sidinga ukuqonda izakhiwo zazo, izinhlelo zokusebenza, izinzuzo, ukungalungi, kanye nezimo zokusebenzisa ezingase zibe khona. Kokubili okuphuma ku-cellulose kusetshenziswa kabanzi ezimbonini ezahlukahlukene, kufaka phakathi ezemithi, ukudla, izimonyo nezokwakha. Ngayinye inezinto ezihlukile ezibenza bafanelekele izinhloso ezahlukene. Masenze ukuqhathanisa okujulile ukuze sibone ukuthi iyiphi engcono ezimeni ezahlukene.
1. Incazelo nesakhiwo:
I-CMC (carboxymethylcellulose): I-CMC iphuma ku-cellulose encibilika emanzini ekhiqizwa ukusabela kwe-cellulose ne-chloroacetic acid. Iqukethe amaqembu e-carboxymethyl (-CH2-COOH) ahlanganiswe namanye amaqembu e-hydroxyl we-glucopyranose monomers akha umgogodla we-cellulose.
I-HPMC (i-hydroxypropyl methylcellulose): I-HPMC futhi iphuma ku-cellulose encibilika emanzini ekhiqizwa ngokwelapha i-cellulose nge-propylene oxide ne-methyl chloride. Iqukethe i-hydroxypropyl kanye namaqembu e-methoxy axhunywe kumgogodla we-cellulose.
2. Ukunyibilika:
I-CMC: Incibilika kakhulu emanzini, yakha isixazululo esisobala, ne-viscous. Ibonisa ukuziphatha kokugeleza kwe-pseudoplastic, okusho ukuthi i-viscosity yayo iyancipha ngaphansi kwengcindezi ye-shear.
I-HPMC: Iphinde inyibilike emanzini, yakha isixazululo se-viscous kancane kune-CMC. Iphinde ibonise ukuziphatha kwe-pseudoplastic.
3.Izakhiwo ze-Rheological:
I-CMC: Ibonisa ukuziphatha kokugunda kwe-shear, okusho ukuthi i-viscosity yayo iyehla ngokwenyuka kwezinga lokugunda. Le ndawo iyenza ifanelekele ukusetshenziswa lapho ukujiya kuyadingeka kodwa isixazululo sidinga ukugeleza kalula ngaphansi kokugunda, njengamapende, okokuhlanza kanye nemithi.
I-HPMC: ibonisa ukuziphatha okufanayo kwe-rheological ku-CMC, kodwa i-viscosity yayo ngokuvamile iphezulu ekugxilweni okuphansi. Inezinto ezingcono zokwenza ifilimu, okuyenza ifaneleke izinhlelo zokusebenza ezifana nama-coatings, ama-adhesives kanye nokukhishwa okulawulwayo kwemithi yokwenziwa kwemithi.
4. Ukuzinza:
I-CMC: Ngokuvamile izinzile phezu kwebanga elibanzi le-pH nezinga lokushisa. Ingakwazi ukubekezelela amazinga amaphakathi ama-electrolyte.
I-HPMC: Izinze kakhulu kune-CMC ngaphansi kwezimo ezine-acidic, kodwa ingase ithole i-hydrolysis ngaphansi kwezimo ze-alkaline. Futhi iyazwela kuma-divalent cations, angabangela i-gelation noma imvula.
5. Isicelo:
I-CMC: isetshenziswa kakhulu njenge-thickener, stabilizer kanye ne-ejenti yokugcina amanzi ekudleni (okufana no-ayisikhilimu, isoso), imithi (njengamaphilisi, ukumiswa) nezimboni zezimonyo (ezifana nokhilimu, okokugcoba).
I-HPMC: Isetshenziswa kakhulu ezintweni zokwakha (isb., izinto zokunamathisela zamathayela kasimende, ukhonkolo, udaka), imithi yemithi (isb., amaphilisi akhishwa okulawulwayo, amalungiselelo e-ophthalmic), nezimonyo (isb, amaconsi amehlo, imikhiqizo yokunakekela isikhumba).
6. Ubuthi nokuphepha:
I-CMC: Ivamise ukubonwa njengephephile (i-GRAS) yizinkampani ezilawulayo uma isetshenziswa ngaphakathi kwemikhawulo ethile ekudleni nasezinhlelweni zemithi. I-biodegradable futhi ayinabo ubuthi.
I-HPMC: Iphinde ithathwe njengephephile ukuthi isetshenziswe ngaphakathi kwemikhawulo enconyiwe. I-biocompatible futhi isetshenziswa kabanzi emkhakheni wezokwelapha njenge-ejenti yokukhululwa elawulwayo kanye nesibophezelo sethebhulethi.
7. Izindleko Nokutholakala:
I-CMC: Ivamise ukubiza kakhulu kune-HPMC. Itholakala kalula kubahlinzeki abahlukahlukene emhlabeni jikelele.
I-HPMC: Ibiza kancane ngenxa yenqubo yokukhiqiza futhi ngezinye izikhathi ukunikezwa okulinganiselwe okuvela kubahlinzeki abathile.
8. Umthelela wemvelo:
I-CMC: I-biodegradable, etholakala ezinsizeni ezivuselelekayo (cellulose). Kubhekwa njengobungani bemvelo.
I-HPMC: Iphinde ibe yi-biodegradable futhi isuselwa ku-cellulose, ngakho-ke futhi inobungani bemvelo.
Kokubili i-CMC ne-HPMC zinezakhiwo ezihlukile ezizenza izithasiselo ezibalulekile ezimbonini eziningi. Ukukhetha phakathi kwabo kuncike ezidingweni ezithile zohlelo lokusebenza ezifana ne-solubility, viscosity, ukuzinza nokucatshangelwa kwezindleko. Ngokuvamile, i-CMC ingakhethwa ngenxa yezindleko zayo eziphansi, ukuzinza okubanzi kwe-pH, nokufaneleka kokudla nezimonyo zokusebenza. I-HPMC, ngakolunye uhlangothi, ingase ithandeke ngenxa ye-viscosity yayo ephezulu, izakhiwo ezingcono zokwenza amafilimu, kanye nokusetshenziswa kwemithi nezinto zokwakha. Ekugcineni, ukukhetha kufanele kusekelwe ekucabangeni okuphelele kwalezi zici kanye nokuhambisana nokusetshenziswa okuhlosiwe.
Isikhathi sokuthumela: Feb-21-2024