IHydroxypropyl methylcellulose (HPMC) iyi-polymer eguquguqukayo esetshenziswa kabanzi ezimbonini ezahlukahlukene ngenxa yezakhiwo nemisebenzi yayo ehlukile.Le polymer ye-semi-synthetic isuselwa ku-cellulose, i-polymer yemvelo etholakala ezindongeni zamaseli ezitshalo.I-HPMC ikhiqizwa ngokushintsha i-cellulose ngokusebenzisa i-etherification ye-propylene oxide ne-methyl chloride.I-polymer ewumphumela ibonisa uhla lwezindawo ezifiselekayo, iyenze ifanele ukusetshenziswa okuhlukahlukene.Lolu hlu olubanzi lokusetshenziswa lungabangelwa ikhono layo lokwenza ifilimu, izakhiwo ezishubile, ukuzinza ezindaweni ezihlukene kanye nokuvumelana kwezinto eziphilayo.
1. Imboni yezemithi
A. Ukuphatha ngomlomo:
Ukukhishwa okulawulwayo: I-HPMC ivamise ukusetshenziselwa ukulethwa kwezidakamizwa ezikhishwayo ekwakhiweni kwemithi.Yakha i-matrix ezinzile evumela ukukhishwa okulawulwayo kwezidakamizwa esikhathini eside, ngaleyo ndlela kuthuthukiswe ukusebenza kahle kokwelapha nokuthobela isiguli.
Isibophezelo sethebhulethi: I-HPMC isebenza njengesibophezelo sethebhulethi esisebenza ngempumelelo futhi isiza ekukhiqizeni amaphilisi anamandla omshini amahle kanye nezakhiwo zokuhlakazeka.
I-ejenti yokumiswa: Kumafomu omthamo owuketshezi, i-HPMC isebenza njenge-ejenti elengayo, ivimbela izinhlayiya ukuthi zingahlali futhi iqinisekise ukusatshalaliswa okufanayo komuthi.
B. Izicelo ze-Ophthalmic:
I-Viscosity Modifier: I-HPMC isetshenziselwa ukulungisa i-viscosity yamaconsi iso ukuze inikeze ukuthambisa okufanele nokuqinisekisa isikhathi eside sokuthintana endaweni yamehlo.
Abadali befilimu: basetshenziselwa ukukhiqiza izifihla-buso noma izinto ezifakwayo ukuze kukhishwe izidakamizwa esweni.
C. Amalungiselelo ezihloko:
Ukwakhiwa Kwejeli: I-HPMC isetshenziselwa ukulungisa amajeli esihloko anikeza ukuthungwa okubushelelezi, okunganamafutha futhi athuthukise ukuthobela kwesiguli.
Izinamatheliso zesikhumba: Ezinhlelweni zokulethwa kwezidakamizwa ze-transdermal, i-HPMC inikeza izici zokunamathela futhi ilawula ukukhishwa kwezidakamizwa ngesikhumba.
D. Izimila Ezingaboli:
Impahla ye-scaffold: I-HPMC isetshenziselwa ukwakha izimila ezingaboli ezilawula ukukhishwa kwezidakamizwa emzimbeni, okuqeda isidingo sokususwa ngokuhlinzwa.
2. Imboni yezokwakha
A. Okunamathelayo Kwethayela:
I-Thickener: I-HPMC isetshenziswa njenge-thickener kuma-adhesives we-tile ukunikeza ukungaguquguquki okudingekayo ukuze kusetshenziswe kalula.
Ukugcinwa Kwamanzi: Kuthuthukisa ukugcinwa kwamanzi kwe-adhesive, kuvimbele ukuthi kumiswe ngokushesha futhi kuqinisekiswe ukuphulukiswa okufanele.
B. Udaka lukasimende:
Ukusebenza kahle: I-HPMC isebenza njengesiguquli se-rheology ukuvimbela ukuhlukaniswa nokuthuthukisa ukubopha, ngaleyo ndlela ithuthukise ukusebenza kodaka olusekelwe kusimende.
Ukugcinwa Kwamanzi: Ngokufana nokunamathelisa amathayili, kusiza ukugcina umswakama engxubeni kasimende, okuvumela ukugeleza kwamanzi ngendlela efanele kanye nokuthuthukiswa kwamandla.
3. imboni yokudla
A. Izithasiselo zokudla:
Ama-thickeners nama-Stabilizers: I-HPMC isetshenziswa njenge-thickener kanye nesiqinisi emikhiqizweni yokudla ehlukahlukene, njengamasoso, okokugqoka kanye nama-dessert.
Indawo yamafutha: Ekudleni okunamafutha amancane noma okungenawo amafutha, i-HPMC ingasetshenziswa esikhundleni samafutha ukuze kuthuthukiswe ukuthungwa nokuzwakala komlomo.
4. Imboni yezimonyo
A. Imikhiqizo yokunakekelwa komuntu siqu:
I-Viscosity Control: I-HPMC isetshenziswa ekwakhiweni kwezimonyo njengamafutha okugcoba nokhilimu ukulawula i-viscosity nokuthuthukisa ukuthungwa sekukonke.
Abadali befilimu: Usizo lokwenza ifilimu emikhiqizweni yokunakekelwa kwezinwele, lunikeze ungqimba oluvikelayo.
5. Ezinye izinhlelo zokusebenza
A. Uyinki wokuphrinta:
I-Thickener: I-HPMC isetshenziswa njenge-thickener koyinki wokuphrinta osuselwe emanzini ukusiza ukufeza ukuvumelana okufiswayo nokuzinza kukayinki.
B. Imikhiqizo enamathelayo:
Thuthukisa i-viscosity: Ekwakheni okunamathelayo, i-HPMC ingangezwa ukuze kuthuthukiswe i-viscosity futhi kuthuthukiswe izakhiwo zokubopha.
5. ekuphetheni
Ukusetshenziswa okuhlukahlukene kwe-HPMC ezimbonini ezahlukahlukene kugqamisa ukuguquguquka nokusebenza kwayo.Ukusetshenziswa kwayo kwezemithi, ukwakhiwa, ukudla, izimonyo nakweminye imikhakha kubonisa inhlanganisela yayo eyingqayizivele yezakhiwo, okuhlanganisa ikhono lokwenza ifilimu, izakhiwo ezijiyayo nokuzinza.Njengoba ubuchwepheshe nocwaningo luthuthuka, i-HPMC kungenzeka iqhubeke nokubamba iqhaza elibalulekile ekuthuthukisweni kwemikhiqizo emisha nokwakheka emikhakheni ehlukene.
Isikhathi sokuthumela: Feb-07-2024