Intengo ka-2019 Advanced Drug Coating kanye ne-Controlled Release Agent
Ukunamathela embonweni othi "Ukudala imikhiqizo yekhwalithi ephezulu kanye nokukhiqiza ubungane nabantu namuhla abavela emhlabeni wonke", sihlala sibeka isifiso sabathengi ukuqala ngenani lentengo ka-2019 I-Advanced Drug Coating and Controlled Release Agent, Sihlala njalo sibheke ukusungula ubudlelwano nabahlinzeki abasha ukuze sinikeze isisombululo esisha nesihlakaniphile kumakhasimende ethu abalulekile.
Ukunamathela embonweni "wokudala imikhiqizo yekhwalithi ephezulu nokukhiqiza ubungane nabantu namuhla abavela kuwo wonke umhlaba", sihlala sibeka isifiso sabathengi ukuqala ngaboI-Pharmacoat HPMC, Siphikelela esimisweni esithi “Isikweletu sibe esiyinhloko, Amakhasimende eyinkosi futhi Ikhwalithi ibe engcono kakhulu”, besibheke ngabomvu ukubambisana nabo bonke abangani ekhaya nabaphesheya futhi sizokwakha ikusasa eliqhakazile ibhizinisi.
Incazelo Yomkhiqizo
IHydroxypropyl Methyl Cellulose(HPMC)
I-Molecular Formula
I-Hypromellose (Hydroxypropylmethylcellulose: HPMC) uhlobo lokufaka esikhundleni 2910, 2906, 2208 (USP)
Izakhiwo Zomzimba
- Impushana emhlophe noma ephuzi emhlophe
- Incibilika ku-solvent exubile yemvelo noma enamanzi
- Ukwenza ifilimu esobala lapho kususwa i-solvent
- Akukho ukusabela kwamakhemikhali nesidakamizwa ngenxa yempahla yayo engeyona i-ionic
- Isisindo samangqamuzana: 10,000 ~ 1,000,000
Iphuzu leGel: 40 ~ 90 ℃
- Indawo yokuthungela ngokuzenzakalelayo: 360 ℃
IHydroxypropyl Methylcellulose (HPMC) Ibanga Lemithi i-Hypromellose excipient kanye nesengezo, esingasetshenziswa njenge-thickener, dispersant, emulsifier kanye ne-ejenti yokwakha ifilimu.
I-QualiCell Cellulose ether iqukethe i-methyl cellulose (USP, EP,BP,CP) kanye nezinhlobo ezintathu esikhundleni se-hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) ngayinye etholakala emabangeni amaningana ahlukene nge-viscosity.Imikhiqizo ye-HPMC ithathwe ku-natural refined I-linter kakotini ne-pulp yokhuni, ehlangabezana nazo zonke izidingo ze-USP, EP, BP, kanye Nezitifiketi ze-Kosher ne-Halal.
Enqubweni yokukhiqiza, ukotini wemvelo ohlanjululwe kakhulu ufakwa etherified nge-methyl chloride noma ngenhlanganisela ye-methyl chloride ne-propylene oxide ukuze kwakheke i-ether encibilika emanzini, engeyona ionic cellulose.Azikho izinsiza zezilwane ezisetshenziswa ekukhiqizweni kwe-HPMC.HPMC engasetshenziswa njengesihlanganisi kumafomu omthamo oqinile njengamaphilisi nama-granules.Iphinde isebenze imisebenzi ehlukahlukene, njengezibonelo, ekuthuthukiseni ukugcinwa kwamanzi, ukuqina, ukusebenza njenge-colloid evikelayo ngenxa yomsebenzi wayo ongaphezulu, ukukhululwa okuqhubekayo, nokwakheka kwefilimu.
I-QualiCell HPMC inikeza imisebenzi ehlukahlukene njengokugcinwa kwamanzi, i-colloid evikelayo, umsebenzi ongaphezulu, ukukhululwa okuqhubekayo.Kuyinhlanganisela engeyona i-ionic imelana nokufakwa kukasawoti ngaphandle futhi izinzile phezu kwebanga elibanzi le-pH.Izinhlelo ezijwayelekile ze-HPMC ziyi-binder kumafomu omthamo oqinile njengamaphilisi nama-granules noma ukuqina kwezinhlelo eziwuketshezi.
I-Pharma HPMC iza ngobubanzi obuhlukahlukene be-viscosity kusuka ku-3 kuye ku-200,000 cps, futhi ingasetshenziswa kabanzi ukuhlanganisa ithebhulethi, imbudumbudu, ibhinder, i-thickener, stabilizer nokwenza i-capsule yemifino ye-HPMC.
Ukucaciswa Kwekhemikhali
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Ibanga Lomkhiqizo
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Isicelo
I-Pharma Grade HPMC inika amandla ukukhiqizwa kokwakhiwa kokukhishwa okulawulwayo ngokunethezeka kwendlela esetshenziswa kakhulu kunazo zonke yokubopha amathebulethi.I-Pharma Grade inikeza ukugeleza kwempushana okuhle, ukufana kokuqukethwe, nokucindezelwa, okuwenza afanelekele ukucindezelwa okuqondile.
| Isicelo se-Pharma Excipients | Pharma Grade HPMC | Isikali |
| I-Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Amakhilimu, Gel | 60E4000,75K4000 | 1-5% |
| Ukulungiselela Ophthalmic | 60E4000 | 01.-0.5% |
| Eye Drop Amalungiselelo | 60E4000 | 0.1-0.5% |
| Umenzeli Omisiwe | 60E4000, 75K4000 | 1-2% |
| Ama-Antacids | 60E4000, 75K4000 | 1-2% |
| I-Tablet Binder | 60E5, 60E15 | 0.5-5% |
| Umhlangano Wet Granulation | 60E5, 60E15 | 2-6% |
| I-Tablet Coatings | 60E5, 60E15 | 0.5-5% |
| I-Matrix yokukhishwa elawulwayo | 75K100000,75K15000 | 20-55% |
Izici Nezinzuzo
- Ithuthukisa izici zokugeleza komkhiqizo
- Yehlisa izikhathi zokucubungula
- Amaphrofayili wokuqedwa afanayo, azinzile
- Ithuthukisa ukufana kokuqukethwe
- Yehlisa izindleko zokukhiqiza
- Igcina amandla okuqina ngemuva kwenqubo yokuhlangana kabili (i-roller compaction).
Ukupakisha
Ukupakisha okujwayelekile kungu-25kg/drum
I-20'FCL: amathani ayi-9 ane-palletized;10 amathani unpalleted.
I-40'FCL: amathani ayi-18 ane-palletized;amathani angama-20 angabhalwanga phansi. Sibambelele ekuqondeni "Ukudala imikhiqizo yekhwalithi ephezulu nokukhiqiza ubungane nabantu namuhla abavela kuwo wonke umhlaba", sihlala sibeka isifiso sabathengi sokuqala ngenani lentengo ka-2019 I-Advanced Drug Coating and Controlled Release Agent, Siphinde sibheke njalo ukwakha ubudlelwano nabahlinzeki abasha ukuze sinikeze isixazululo esisha nesihlakaniphile kumakhasimende ethu abalulekile.
Intengo ye-wholesale yango-2019I-Pharmacoat HPMC, Siphikelela esimisweni esithi “Isikweletu sibe esiyinhloko, Amakhasimende eyinkosi futhi Ikhwalithi ibe engcono kakhulu”, besibheke ngabomvu ukubambisana nabo bonke abangani ekhaya nabaphesheya futhi sizokwakha ikusasa eliqhakazile ibhizinisi.
