Ikhwalithi Enhle Kakhulu Yefekthri Ukugcinwa Kwamanzi Okuphezulu kanye ne-HPMC Ye-Viscosity Ephakeme Yokwakha
Sihlinzeka ngokuqina okuhle kakhulu ekuthuthukisweni okuhle nokuthuthuka, ukuthengisa, ukuthengisa okuphelele nokuphromotha nokusebenza Kwekhwalithi Enhle Kakhulu Yefekthri Ukugcinwa Kwamanzi Aphakeme kanye ne-High Viscosity HPMC Yokwakha, Ngomzamo weminyaka eyi-10, siheha amathemba ngezindleko ezinolaka kanye nomhlinzeki omuhle kakhulu. Ngaphezu kwalokho, kuyiqiniso nobuqotho bethu, okusisiza ukuba sibe ukukhetha kokuqala kwamaklayenti njalo.
Sihlinzeka ngokuqina okuhle kakhulu nokuthuthuka, ukuthengisa, ukuthengisa okuphelele nokuphromotha nokusebenza kweI-China Coating Auxiliary Agents kanye Nezinto Zokwakha, Inkampani yethu izobambelela kufilosofi yebhizinisi "Ikhwalithi kuqala,, ukuphelela kuze kube phakade, okuqondiswe kubantu, ukusungulwa kwezobuchwepheshe". Ukusebenza kanzima ukuze uqhubeke nokwenza inqubekelaphambili, ukuqamba okusha embonini, yenza yonke imizamo ebhizinisini elisezingeni lokuqala. Sizama konke okusemandleni ethu ukwakha imodeli yokuphatha yesayensi, ukufunda ulwazi oluningi abanamakhono, ukuthuthukisa imishini yokukhiqiza ethuthukisiwe kanye nenqubo yokukhiqiza, ukudala izixazululo zekhwalithi yocingo lokuqala, intengo enengqondo, ikhwalithi ephezulu yesevisi, ukulethwa okusheshayo, ukukunikeza ukudala inani elisha .
Incazelo Yomkhiqizo
IHydroxypropyl Methyl Cellulose(HPMC)
I-Molecular Formula
I-Hypromellose (Hydroxypropylmethylcellulose: HPMC) uhlobo lokufaka esikhundleni 2910, 2906, 2208 (USP)
Izakhiwo Zomzimba
- Impushana emhlophe noma ephuzi emhlophe
- Incibilika ku-solvent exubile yemvelo noma enamanzi
- Ukwenza ifilimu esobala lapho kususwa i-solvent
- Akukho ukusabela kwamakhemikhali nesidakamizwa ngenxa yempahla yayo engeyona i-ionic
- Isisindo samangqamuzana: 10,000 ~ 1,000,000
Iphuzu leGel: 40 ~ 90 ℃
- Indawo yokuthungela ngokuzenzakalelayo: 360 ℃
IHydroxypropyl Methylcellulose (HPMC) Ibanga Lemithi i-Hypromellose excipient kanye nesengezo, esingasetshenziswa njenge-thickener, dispersant, emulsifier kanye ne-ejenti yokwakha ifilimu.
I-QualiCell Cellulose ether iqukethe i-methyl cellulose (USP, EP,BP,CP) kanye nezinhlobo ezintathu esikhundleni se-hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) ngayinye etholakala emabangeni amaningana ahlukene nge-viscosity.Imikhiqizo ye-HPMC ithathwe ku-natural refined I-linter kakotini kanye ne-pulp yokhuni, ehlangabezana nazo zonke izidingo ze-USP, EP, BP, kanye ne-Kosher kanye Izitifiketi ze-Halal.
Enqubweni yokukhiqiza, ukotini wemvelo ohlanjululwe kakhulu ufakwa etherified nge-methyl chloride noma ngenhlanganisela ye-methyl chloride ne-propylene oxide ukuze kwakheke i-ether encibilika emanzini, engeyona ionic cellulose. Azikho izinsiza zezilwane ezisetshenziswa ekukhiqizweni kwe-HPMC.HPMC engasetshenziswa njengesihlanganisi kumafomu omthamo oqinile njengamaphilisi nama-granules. Iphinde isebenze imisebenzi ehlukahlukene, njengezibonelo, ekuthuthukiseni ukugcinwa kwamanzi, ukuqina, ukusebenza njenge-colloid evikelayo ngenxa yomsebenzi wayo ongaphezulu, ukukhululwa okuqhubekayo, nokwakheka kwefilimu.
I-QualiCell HPMC inikeza imisebenzi ehlukahlukene njengokugcinwa kwamanzi, i-colloid evikelayo, umsebenzi ongaphezulu, ukukhululwa okuqhubekayo. Kuyinhlanganisela engeyona i-ionic imelana nokufakwa kukasawoti ngaphandle futhi izinzile phezu kwebanga elibanzi le-pH. Izinhlelo ezijwayelekile ze-HPMC ziyi-binder kumafomu omthamo oqinile njengamaphilisi nama-granules noma ukuqina kwezinhlelo eziwuketshezi.
I-Pharma HPMC iza ngobubanzi obuhlukahlukene be-viscosity kusuka ku-3 kuye ku-200,000 cps, futhi ingasetshenziswa kabanzi ukuhlanganisa ithebhulethi, imbudumbudu, ibhinder, i-thickener, stabilizer nokwenza i-capsule yemifino ye-HPMC.
Ukucaciswa Kwekhemikhali
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Ibanga Lomkhiqizo
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Isicelo
I-Pharma Grade HPMC inika amandla ukukhiqizwa kokwakhiwa kokukhishwa okulawulwayo ngokunethezeka kwendlela esetshenziswa kakhulu kunazo zonke yokubopha amathebulethi. I-Pharma Grade inikeza ukugeleza kwempushana okuhle, ukufana kokuqukethwe, nokucindezelwa, okuwenza afanelekele ukucindezelwa okuqondile.
| Isicelo se-Pharma Excipients | Pharma Grade HPMC | Umthamo |
| I-Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Amakhilimu, amaGel | 60E4000,75K4000 | 1-5% |
| Ukulungiselela Ophthalmic | 60E4000 | 01.-0.5% |
| Eye Drop Amalungiselelo | 60E4000 | 0.1-0.5% |
| Umenzeli Omisiwe | 60E4000, 75K4000 | 1-2% |
| Ama-Antacids | 60E4000, 75K4000 | 1-2% |
| I-Tablet Binder | 60E5, 60E15 | 0.5-5% |
| Umhlangano Wet Granulation | 60E5, 60E15 | 2-6% |
| I-Tablet Coatings | 60E5, 60E15 | 0.5-5% |
| I-Matrix yokukhishwa elawulwayo | 75K100000,75K15000 | 20-55% |
Izici Nezinzuzo
- Ithuthukisa izici zokugeleza komkhiqizo
- Yehlisa izikhathi zokucubungula
- Amaphrofayili wokuqedwa afanayo, azinzile
- Ithuthukisa ukufana kokuqukethwe
- Yehlisa izindleko zokukhiqiza
- Igcina amandla okuqina ngemuva kwenqubo yokuhlangana kabili (i-roller compaction).
Ukupakisha
Ukupakisha okujwayelekile kungu-25kg/drum
I-20'FCL: amathani ayi-9 ane-palletized; 10 ton unpalleted.
I-40'FCL: amathani ayi-18 ane-palletized; 20 ton unpalletized.Sihlinzeka ngokuqina okuhle kakhulu nokuthuthuka, ukuthengisa, ukuthengisa okuphelele nokuphromotha nokusebenza kwekhwalithi Enhle Kakhulu Yefekthri Ukugcinwa Kwamanzi Okuphezulu kanye ne-High Viscosity HPMC Yokwakha, Ngomzamo weminyaka eyi-10, siheha amathemba ngezindleko ezinolaka kanye nomhlinzeki omuhle kakhulu. . Ngaphezu kwalokho, kuyiqiniso nobuqotho bethu, okusisiza ukuba sibe ukukhetha kokuqala kwamaklayenti njalo.
Ikhwalithi enhle kakhuluI-China Coating Auxiliary Agents kanye Nezinto Zokwakha, Inkampani yethu izobambelela kufilosofi yebhizinisi "Ikhwalithi kuqala,, ukuphelela kuze kube phakade, okuqondiswe kubantu, ukusungulwa kwezobuchwepheshe". Ukusebenza kanzima ukuze uqhubeke nokwenza inqubekelaphambili, ukuqamba okusha embonini, yenza yonke imizamo ebhizinisini elisezingeni lokuqala. Sizama konke okusemandleni ethu ukwakha imodeli yokuphatha yesayensi, ukufunda ulwazi oluningi abanamakhono, ukuthuthukisa imishini yokukhiqiza ethuthukisiwe kanye nenqubo yokukhiqiza, ukudala izixazululo zekhwalithi yocingo lokuqala, intengo enengqondo, ikhwalithi ephezulu yesevisi, ukulethwa okusheshayo, ukukunikeza ukudala inani elisha .
