I-HPMC E15-Ikhwalithi enhle kakhulu i-HPMC E3 E5 E6 E15 E50 K100m (Inombolo ye-CAS: 9004-65-3) USP/Ep/Bp
Ibambelela emfundisweni ethi “Thembeka, ikhuthele, iyathakazelisa, entsha” ukuthuthukisa imikhiqizo emisha nezisombululo ngokuqhubekayo. Ibheka abathengi, impumelelo njengempumelelo yomuntu ngamunye. Masikhiqize isandla esinekusasa eliphumelelayo esandleni se-HPMC E15-Ikhwalithi ephezulu kakhulu ye-HPMC E3 E5 E6 E15 E50 K100m (Inombolo ye-CAS: 9004-65-3) USP/Ep/Bp, Ngemibuzo eyengeziwe noma kufanele ube nanoma yimuphi umbuzo mayelana nezisombululo zethu, ngokuvamile akufanele ulinde ukukhuluma nathi.
Ibambelela emfundisweni ethi “Thembeka, ikhuthele, iyathakazelisa, entsha” ukuthuthukisa imikhiqizo emisha nezisombululo ngokuqhubekayo. Ibheka abathengi, impumelelo njengempumelelo yomuntu ngamunye. Masikhiqizele ikusasa elichumayo ngesandlaIHydroxypropyl Methyl Cellulose kanye ne-HPMC, Ukwaneliseka kwekhasimende kuwumgomo wethu wokuqala. Umgomo wethu ukuphishekela ikhwalithi ephezulu kakhulu, senze inqubekelaphambili eqhubekayo. Siyakwamukela ngokuzithoba ukuthi nenze inqubekela phambili nibambene nathi, futhi sakhe ikusasa eliqhakazile ndawonye.
Incazelo Yomkhiqizo
IHydroxypropyl Methyl Cellulose(HPMC)
I-Molecular Formula
I-Hypromellose (Hydroxypropylmethylcellulose: HPMC) uhlobo lokufaka esikhundleni 2910, 2906, 2208 (USP)
Izakhiwo Zomzimba
- Impushana emhlophe noma ephuzi emhlophe
- Incibilika ku-solvent exubile yemvelo noma enamanzi
- Ukwenza ifilimu esobala lapho kususwa i-solvent
- Akukho ukusabela kwamakhemikhali nesidakamizwa ngenxa yempahla yayo engeyona i-ionic
- Isisindo samangqamuzana: 10,000 ~ 1,000,000
Iphuzu leGel: 40 ~ 90 ℃
- Indawo yokuthungela ngokuzenzakalelayo: 360 ℃
IHydroxypropyl Methylcellulose (HPMC) Ibanga Lemithi i-Hypromellose excipient kanye nesengezo, esingasetshenziswa njenge-thickener, dispersant, emulsifier kanye ne-ejenti yokwakha ifilimu.
I-QualiCell Cellulose ether iqukethe i-methyl cellulose (USP, EP,BP,CP) kanye nezinhlobo ezintathu esikhundleni se-hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) ngayinye etholakala emabangeni amaningana ahlukene nge-viscosity.Imikhiqizo ye-HPMC ithathwe ku-natural refined I-linter kakotini ne-pulp yokhuni, ehlangabezana nazo zonke izidingo ze-USP, i-EP, i-BP, kanye Nezitifiketi ze-Kosher ne-Halal.
Enqubweni yokukhiqiza, ukotini wemvelo ohlanjululwe kakhulu ufakwa etherified nge-methyl chloride noma ngenhlanganisela ye-methyl chloride ne-propylene oxide ukuze kwakheke i-ether encibilika emanzini, engeyona ionic cellulose. Azikho izinsiza zezilwane ezisetshenziswa ekukhiqizweni kwe-HPMC.HPMC engasetshenziswa njengesihlanganisi kumafomu omthamo oqinile njengamaphilisi nama-granules. Iphinde isebenze imisebenzi ehlukahlukene, njengezibonelo, ekuthuthukiseni ukugcinwa kwamanzi, ukuqina, ukusebenza njenge-colloid evikelayo ngenxa yomsebenzi wayo ongaphezulu, ukukhululwa okuqhubekayo, nokwakheka kwefilimu.
I-QualiCell HPMC inikeza imisebenzi ehlukahlukene njengokugcinwa kwamanzi, i-colloid evikelayo, umsebenzi ongaphezulu, ukukhululwa okuqhubekayo. Kuyinhlanganisela engeyona i-ionic imelana nokufakwa kukasawoti ngaphandle futhi izinzile phezu kwebanga elibanzi le-pH. Izinhlelo ezijwayelekile ze-HPMC ziyi-binder kumafomu omthamo oqinile njengamaphilisi nama-granules noma ukuqina kokusetshenziswa koketshezi.
I-Pharma HPMC iza ngobubanzi obuhlukahlukene be-viscosity kusuka ku-3 kuye ku-200,000 cps, futhi ingasetshenziswa kabanzi ukuhlanganisa ithebhulethi, imbudumbudu, ibhinder, i-thickener, stabilizer nokwenza i-capsule yemifino ye-HPMC.
Ukucaciswa Kwekhemikhali
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Ibanga Lomkhiqizo
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Isicelo
I-Pharma Grade HPMC inika amandla ukukhiqizwa kokwakhiwa kokukhishwa okulawulwayo ngokunethezeka kwendlela esetshenziswa kakhulu kunazo zonke yokubopha amathebulethi. I-Pharma Grade inikeza ukugeleza kwempushana okuhle, ukufana kokuqukethwe, nokucindezelwa, okuwenza afanelekele ukucindezelwa okuqondile.
| Isicelo se-Pharma Excipients | Pharma Grade HPMC | Umthamo |
| I-Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Amakhilimu, Gel | 60E4000,75K4000 | 1-5% |
| Ukulungiselela Ophthalmic | 60E4000 | 01.-0.5% |
| Eye Drop Amalungiselelo | 60E4000 | 0.1-0.5% |
| Umenzeli Omisiwe | 60E4000, 75K4000 | 1-2% |
| Ama-Antacids | 60E4000, 75K4000 | 1-2% |
| I-Tablet Binder | 60E5, 60E15 | 0.5-5% |
| Umhlangano Wet Granulation | 60E5, 60E15 | 2-6% |
| I-Tablet Coatings | 60E5, 60E15 | 0.5-5% |
| I-Matrix yokukhishwa elawulwayo | 75K100000,75K15000 | 20-55% |
Izici Nezinzuzo
- Ithuthukisa izici zokugeleza komkhiqizo
- Yehlisa izikhathi zokucubungula
- Amaphrofayili wokuqedwa afanayo, azinzile
- Ithuthukisa ukufana kokuqukethwe
- Yehlisa izindleko zokukhiqiza
- Igcina amandla okuqina ngemuva kwenqubo yokuhlangana kabili (i-roller compaction).
Ukupakisha
Ukupakisha okujwayelekile kungu-25kg/drum
I-20'FCL: amathani ayi-9 ane-palletized; 10 ton unpalleted.
I-40'FCL: amathani ayi-18 ane-palletized; 20 ton unpalletized.Ibambelela emfundisweni ethi “Thembeka, ikhuthele, iyathakazelisa, iqanjwe kabusha” ukuthuthukisa imikhiqizo emisha nezisombululo ngokuqhubekayo. Ibheka abathengi, impumelelo njengempumelelo yomuntu ngamunye. Masikhiqize isandla esinekusasa eliphumelelayo esandleni sekhwalithi Enhle Kakhulu i-HPMC E3 E5 E6 E15 E50 K100m (CAS No: 9004-65-3) USP/Ep/Bp, Ngemibuzo eyengeziwe noma uma unombuzo mayelana nezisombululo zethu, ngokuvamile kufanele ungalindi ukukhuluma lathi.
Ikhwalithi enhle kakhuluIHydroxypropyl Methyl Cellulose kanye ne-HPMC, Ukwaneliseka kwekhasimende kuwumgomo wethu wokuqala. Umgomo wethu ukuphishekela ikhwalithi ephezulu kakhulu, senze inqubekelaphambili eqhubekayo. Siyakwamukela ngokuzithoba ukuthi nenze inqubekela phambili nibambene nathi, futhi sakhe ikusasa eliqhakazile ndawonye.
