Yethula:
IHydroxypropylmethylcellulose (HPMC) kanye ne-hydroxyethylcellulose (HEC) zombili izithasiselo ezisetshenziswa kakhulu embonini yokudla, yezimonyo neyokwenza imithi. Lezi zinto eziphuma ku-cellulose zinethuba elibanzi lokusetshenziswa ngenxa yokuncibilika kwamanzi okuyingqayizivele, ukuqina kokuqina, nekhono elihle kakhulu lokwenza ifilimu.
1.Isakhiwo samakhemikhali:
I-HPMC iyi-polymer yokwenziwa etholakala ku-cellulose. Yenziwa ngokushintsha i-cellulose yemvelo ngamakhemikhali ngokungeza i-propylene oxide ne-methyl chloride. I-HEC iphinde ibe uhlobo lokuphuma kwe-cellulose, kodwa yenziwa ngokusabela i-cellulose yemvelo nge-ethylene oxide bese iphathwa nge-alkali.
2. Ukunyibilika:
Kokubili i-HPMC ne-HEC ayancibilika emanzini futhi angancibilika emanzini abandayo. Kodwa i-solubility ye-HEC iphansi kune-HPMC. Lokhu kusho ukuthi i-HPMC inokuhlakazeka okungcono futhi ingasetshenziswa kalula ekwenziweni.
3. I-Viscosity:
I-HPMC kanye ne-HEC banezici ezihlukile ze-viscosity ngenxa yezakhiwo zabo zamakhemikhali. I-HEC inesisindo samangqamuzana esiphezulu nesakhiwo esiminyene kune-HPMC, esinikeza i-viscosity ephakeme. Ngakho-ke, i-HEC ivame ukusetshenziswa njenge-thickener ekwakhiweni okudinga i-viscosity ephezulu, kuyilapho i-HPMC isetshenziselwa ukwakheka okudinga i-viscosity ephansi.
4. Ukusebenza kokwenza ifilimu:
Kokubili i-HPMC ne-HEC banamakhono amahle kakhulu okwenza ifilimu. Kodwa i-HPMC inezinga lokushisa eliphansi lokwenza ifilimu, okusho ukuthi lingasetshenziswa emazingeni okushisa aphansi. Lokhu kwenza i-HPMC ifaneleke kakhulu ukusetshenziswa ekuhlanganiseni okudinga izikhathi zokumisa ngokushesha nokunamathela okungcono.
5. Ukuzinza:
I-HPMC ne-HEC zizinzile ngaphansi kwezimo eziningi ze-pH nezinga lokushisa. Nokho, i-HEC izwela kakhulu ekushintsheni kwe-pH kune-HPMC. Lokhu kusho ukuthi i-HEC kufanele isetshenziswe ekuhlanganiseni okunebanga le-pH lika-5 kuya ku-10, kuyilapho i-HPMC ingasetshenziswa ebangeni le-pH elibanzi.
6. Isicelo:
Izici ezihlukene ze-HPMC ne-HEC zibenza bafanelekele izinhlelo zokusebenza ezahlukene. I-HEC ivame ukusetshenziswa njenge-ejenti yokuqina ekwakhiweni kwezimonyo nakwezemithi. Ibuye isetshenziswe njenge-binder kanye ne-ejenti yokwakha ifilimu ekwakhiweni kwethebhulethi. I-HPMC isetshenziswa njenge-thickener, stabilizer, kanye ne-ejenti yokwakha ifilimu ekudleni, emithini, nasekwakhekeni kwezimonyo. Ibuye isetshenziswe njenge-ejenti ye-gelling kwezinye izinhlelo zokusebenza zokudla.
Ekuphetheni:
I-HPMC kanye ne-HEC kokubili okuphuma ku-cellulose okunezici ezihlukile ezifanele izinhlelo zokusebenza ezahlukene. Ukuqonda umehluko phakathi kwalezi zithako ezimbili kungakusiza ukhethe okulungile kweresiphi yakho. Sekukonke, i-HPMC ne-HEC ziyizithasiselo eziphephile nezisebenzayo ezinikeza izinzuzo eziningi embonini yokudla, yezimonyo neyokwenza imithi.
Isikhathi sokuthumela: Sep-13-2023