I-HPMC VS HEC: 6 Umehluko Odinga Ukukwazi!

Yethula:

IHydroxypropylmethylcellulose (HPMC) kanye ne-hydroxyethylcellulose (HEC) zombili izithasiselo ezisetshenziswa kakhulu embonini yokudla, yezimonyo neyokwenza imithi.Lezi zinto eziphuma ku-cellulose zinethuba elibanzi lokusetshenziswa ngenxa yokuncibilika kwamanzi okuyingqayizivele, ukuqina kokuqina, nekhono elihle kakhulu lokwenza ifilimu.

1.Isakhiwo samakhemikhali:

I-HPMC iyi-polymer yokwenziwa etholakala ku-cellulose.Yenziwa ngokushintsha i-cellulose yemvelo ngamakhemikhali ngokungeza i-propylene oxide ne-methyl chloride.I-HEC iphinde ibe uhlobo lokuphuma kwe-cellulose, kodwa yenziwa ngokusabela i-cellulose yemvelo nge-ethylene oxide bese iphathwa nge-alkali.

2. Ukunyibilika:

Kokubili i-HPMC ne-HEC ayancibilika emanzini futhi angancibilika emanzini abandayo.Kodwa i-solubility ye-HEC iphansi kune-HPMC.Lokhu kusho ukuthi i-HPMC inokuhlakazeka okungcono futhi ingasetshenziswa kalula ekwenziweni.

3. I-Viscosity:

I-HPMC kanye ne-HEC banezici ezihlukile ze-viscosity ngenxa yezakhiwo zabo zamakhemikhali.I-HEC inesisindo samangqamuzana esiphezulu nesakhiwo esiminyene kune-HPMC, esinikeza i-viscosity ephakeme.Ngakho-ke, i-HEC ivame ukusetshenziswa njenge-thickener ekwakhiweni okudinga i-viscosity ephezulu, kuyilapho i-HPMC isetshenziselwa ukwakheka okudinga i-viscosity ephansi.

4. Ukusebenza kokwenza ifilimu:

Kokubili i-HPMC ne-HEC banamakhono amahle kakhulu okwenza ifilimu.Kodwa i-HPMC inezinga lokushisa eliphansi lokwenza ifilimu, okusho ukuthi lingasetshenziswa emazingeni okushisa aphansi.Lokhu kwenza i-HPMC ifaneleke kakhulu ukusetshenziswa ekuhlanganiseni okudinga izikhathi zokumisa ngokushesha nokunamathela okungcono.

5. Ukuzinza:

I-HPMC ne-HEC zizinzile ngaphansi kwezimo eziningi ze-pH nezinga lokushisa.Nokho, i-HEC izwela kakhulu ekushintsheni kwe-pH kune-HPMC.Lokhu kusho ukuthi i-HEC kufanele isetshenziswe ekuhlanganiseni okunebanga le-pH lika-5 kuya ku-10, kuyilapho i-HPMC ingasetshenziswa ebangeni le-pH elibanzi.

6. Isicelo:

Izici ezihlukene ze-HPMC ne-HEC zibenza bafanelekele izinhlelo zokusebenza ezahlukene.I-HEC ivame ukusetshenziswa njenge-ejenti yokuqina ekwakhiweni kwezimonyo nakwezemithi.Ibuye isetshenziswe njenge-binder kanye ne-ejenti yokwakha ifilimu ekwakhiweni kwethebhulethi.I-HPMC isetshenziswa njenge-thickener, stabilizer, kanye ne-ejenti yokwakha ifilimu ekudleni, emithini, nasekwakhekeni kwezimonyo.Ibuye isetshenziswe njenge-ejenti ye-gelling kwezinye izinhlelo zokusebenza zokudla.

Ekuphetheni:

I-HPMC kanye ne-HEC kokubili okuphuma ku-cellulose okunezici ezihlukile ezifanele izinhlelo zokusebenza ezahlukene.Ukuqonda umehluko phakathi kwalezi zithako ezimbili kungakusiza ukhethe okulungile kweresiphi yakho.Sekukonke, i-HPMC kanye ne-HEC ziyizithasiselo eziphephile nezisebenzayo ezinikeza izinzuzo eziningi ezimbonini zokudla, zezimonyo nezemithi.